Gamma rhythm communication between entorhinal cortex and dentate gyrus neuronal assemblies

Brain region coordination in learning Gamma-frequency oscillations have been hypothesized as a physiological mechanism of interregional communication the brain. However, until now, all supporting data correlational and thus indirect. Fernández-Ruiz et al. examined gamma-frequency activity spike coupling between entorhinal cortex hippocampal dentate gyrus during after selective perturbation timing. They observed an integrated neuron, gamma-band, task-specific organization cortex–hippocampal circuits. These demonstrate that specific, projected oscillation patterns dynamically engage functionally related cell assemblies across brain regions manner. Science , this issue p. eabf3119